Reactions to gamma-irradiation in an acute dose of 750 R in C57BL/6, 101/Hf and С3H/Sn mice at different physiological levels were analyzed. In C3H/Sn and 101/Hf mice, light scattering spectrum was shifted towards small particles, while in C57BL/6 mice increased contribution of large particles was observed. In 3 weeks, a shift towards larger particles was recorded in all three mouse strains, but its degree varied. By week 6, the histograms approached the control. Histological study showed that the incidence of severe injuries in the liver increased by the end of the experiment in C57BL/6 mice (but not in other mouse strains). The same shifts were observed in the pancreas and an opposite tendency was seen in the spleen. Thus, C57BL/6 mice responded to irradiation later that C3H/Sn and 101/Hf mice, but demonstrated high adaptation capacity. C3H/Sn mice best of all recovered from the radiation crisis.
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American Journal of Life Sciences (Volume 3, Issue 1-2)
This article belongs to the Special Issue Space Flight Factors: From Cell to Body |
| DOI | 10.11648/j.ajls.s.2015030102.13 |
| Page(s) | 13-17 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2014. Published by Science Publishing Group |
Irradiation, Strain-Specific Differences, Laser Correlation Spectroscopy, Radiosensitivity
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APA Style
Yulia Medvedeva, Elena Arkhipova, Irina Alchinova. (2014). The Effects of Gamma-Irradiation in Sub-Lethal Doses in Mice with Different Radiosensitivity. American Journal of Life Sciences, 3(1-2), 13-17. https://doi.org/10.11648/j.ajls.s.2015030102.13
ACS Style
Yulia Medvedeva; Elena Arkhipova; Irina Alchinova. The Effects of Gamma-Irradiation in Sub-Lethal Doses in Mice with Different Radiosensitivity. Am. J. Life Sci. 2014, 3(1-2), 13-17. doi: 10.11648/j.ajls.s.2015030102.13
AMA Style
Yulia Medvedeva, Elena Arkhipova, Irina Alchinova. The Effects of Gamma-Irradiation in Sub-Lethal Doses in Mice with Different Radiosensitivity. Am J Life Sci. 2014;3(1-2):13-17. doi: 10.11648/j.ajls.s.2015030102.13
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Download@article{10.11648/j.ajls.s.2015030102.13,
author = {Yulia Medvedeva and Elena Arkhipova and Irina Alchinova},
title = {The Effects of Gamma-Irradiation in Sub-Lethal Doses in Mice with Different Radiosensitivity},
journal = {American Journal of Life Sciences},
volume = {3},
number = {1-2},
pages = {13-17},
doi = {10.11648/j.ajls.s.2015030102.13},
url = {https://doi.org/10.11648/j.ajls.s.2015030102.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.s.2015030102.13},
abstract = {Reactions to gamma-irradiation in an acute dose of 750 R in C57BL/6, 101/Hf and С3H/Sn mice at different physiological levels were analyzed. In C3H/Sn and 101/Hf mice, light scattering spectrum was shifted towards small particles, while in C57BL/6 mice increased contribution of large particles was observed. In 3 weeks, a shift towards larger particles was recorded in all three mouse strains, but its degree varied. By week 6, the histograms approached the control. Histological study showed that the incidence of severe injuries in the liver increased by the end of the experiment in C57BL/6 mice (but not in other mouse strains). The same shifts were observed in the pancreas and an opposite tendency was seen in the spleen. Thus, C57BL/6 mice responded to irradiation later that C3H/Sn and 101/Hf mice, but demonstrated high adaptation capacity. C3H/Sn mice best of all recovered from the radiation crisis.},
year = {2014}
}
TY - JOUR T1 - The Effects of Gamma-Irradiation in Sub-Lethal Doses in Mice with Different Radiosensitivity AU - Yulia Medvedeva AU - Elena Arkhipova AU - Irina Alchinova Y1 - 2014/11/29 PY - 2014 N1 - https://doi.org/10.11648/j.ajls.s.2015030102.13 DO - 10.11648/j.ajls.s.2015030102.13 T2 - American Journal of Life Sciences JF - American Journal of Life Sciences JO - American Journal of Life Sciences SP - 13 EP - 17 PB - Science Publishing Group SN - 2328-5737 UR - https://doi.org/10.11648/j.ajls.s.2015030102.13 AB - Reactions to gamma-irradiation in an acute dose of 750 R in C57BL/6, 101/Hf and С3H/Sn mice at different physiological levels were analyzed. In C3H/Sn and 101/Hf mice, light scattering spectrum was shifted towards small particles, while in C57BL/6 mice increased contribution of large particles was observed. In 3 weeks, a shift towards larger particles was recorded in all three mouse strains, but its degree varied. By week 6, the histograms approached the control. Histological study showed that the incidence of severe injuries in the liver increased by the end of the experiment in C57BL/6 mice (but not in other mouse strains). The same shifts were observed in the pancreas and an opposite tendency was seen in the spleen. Thus, C57BL/6 mice responded to irradiation later that C3H/Sn and 101/Hf mice, but demonstrated high adaptation capacity. C3H/Sn mice best of all recovered from the radiation crisis. VL - 3 IS - 1-2 ER -
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