Phytochemical Evaluation, Anti-obesity and Antihyperlipidemic Effects of Combined Administration of Green Coffee, Cinnamon and Ginger

Gehan Fawzy Abdel Raoof; Khaled Younes Mohamed; Hala Mahmoud Mohammed

doi:doi:10.11648/j.plant.20170505.12

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Phytochemical Evaluation, Anti-obesity and Antihyperlipidemic Effects of Combined Administration of Green Coffee, Cinnamon and Ginger

Gehan Fawzy Abdel Raoof, Khaled Younes Mohamed, Hala Mahmoud Mohammed

Published in Plant (Volume 5, Issue 5)

Received: 8 October 2017 Accepted: 18 October 2017 Published: 8 November 2017

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Abstract

This study aims to evaluate anti-obesity and antihyperlipidemic effects of individual and combined administration of ginger, cinnamon and green coffee on the hyperlipidimic rats. It is the first report dealing with the effects of the combined administration of these three plants as anti-obesity and antihyperlipidemic agents. Sprague-Dawley rats were used, where they divided into 6 groups (7 rats each). Group 1 was kept as a normal control, while the other groups fed on high-fat diet to induce obesity and hyperlipidemia for 4 weeks. Group 2 positive control that was kept obese, while other groups were orally given individual and combined powders of ginger, cinnamon and green coffee in doses 200mg/kg, respectively, for 6 weeks, At the end of the experiment, body weight of rats were recorded. Blood samples were collected for analyses. The results showed that each of individual and combined administration of these plants significantly (P<0.05) decreased the body weight and serum lipids including total lipid, triglyceride and low density lipoprotein when compared with positive control group, while they significantly (P<0.05) increased high density lipoprotein when compared with positive control group. Furthermore, our study showed that the combination of these three plants exhibited better effects than when compared to the individual powder of the plants. In this study we compared the effects of separated and combined administration of cinnamon bark, ginger root, green coffee beans as anti-obesity and antihyperlipidemic agents. The separated and combined administration exhibited significant anti-obesity and antihyperlipidemic effects in obese and hyperlipidemic rats, while the combined administration showed more powerful effects. Previous reports on cinnamon, ginger and green coffee as separately administered were thus confirmed; however, this is, to our knowledge, the first report dealing with the combined form of the three plants. Such combined administration might be useful in developing natural food additives to help address obesity and hyperlipidemia.

Published in	Plant (Volume 5, Issue 5)
DOI	10.11648/j.plant.20170505.12
Page(s)	80-84
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Ginger, Cinnamon, Green Coffee, Lipid, Obesity

References

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APA Style

Gehan Fawzy Abdel Raoof, Khaled Younes Mohamed, Hala Mahmoud Mohammed. (2017). Phytochemical Evaluation, Anti-obesity and Antihyperlipidemic Effects of Combined Administration of Green Coffee, Cinnamon and Ginger. Plant, 5(5), 80-84. https://doi.org/10.11648/j.plant.20170505.12

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ACS Style

Gehan Fawzy Abdel Raoof; Khaled Younes Mohamed; Hala Mahmoud Mohammed. Phytochemical Evaluation, Anti-obesity and Antihyperlipidemic Effects of Combined Administration of Green Coffee, Cinnamon and Ginger. Plant. 2017, 5(5), 80-84. doi: 10.11648/j.plant.20170505.12

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AMA Style

Gehan Fawzy Abdel Raoof, Khaled Younes Mohamed, Hala Mahmoud Mohammed. Phytochemical Evaluation, Anti-obesity and Antihyperlipidemic Effects of Combined Administration of Green Coffee, Cinnamon and Ginger. Plant. 2017;5(5):80-84. doi: 10.11648/j.plant.20170505.12

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@article{10.11648/j.plant.20170505.12,
  author = {Gehan Fawzy Abdel Raoof and Khaled Younes Mohamed and Hala Mahmoud Mohammed},
  title = {Phytochemical Evaluation, Anti-obesity and Antihyperlipidemic Effects of Combined Administration of Green Coffee, Cinnamon and Ginger},
  journal = {Plant},
  volume = {5},
  number = {5},
  pages = {80-84},
  doi = {10.11648/j.plant.20170505.12},
  url = {https://doi.org/10.11648/j.plant.20170505.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.plant.20170505.12},
  abstract = {This study aims to evaluate anti-obesity and antihyperlipidemic effects of individual and combined administration of ginger, cinnamon and green coffee on the hyperlipidimic rats. It is the first report dealing with the effects of the combined administration of these three plants as anti-obesity and antihyperlipidemic agents. Sprague-Dawley rats were used, where they divided into 6 groups (7 rats each). Group 1 was kept as a normal control, while the other groups fed on high-fat diet to induce obesity and hyperlipidemia for 4 weeks. Group 2 positive control that was kept obese, while other groups were orally given individual and combined powders of ginger, cinnamon and green coffee in doses 200mg/kg, respectively, for 6 weeks, At the end of the experiment, body weight of rats were recorded. Blood samples were collected for analyses. The results showed that each of individual and combined administration of these plants significantly (P<0.05) decreased the body weight and serum lipids including total lipid, triglyceride and low density lipoprotein when compared with positive control group, while they significantly (P<0.05) increased high density lipoprotein when compared with positive control group. Furthermore, our study showed that the combination of these three plants exhibited better effects than when compared to the individual powder of the plants. In this study we compared the effects of separated and combined administration of cinnamon bark, ginger root, green coffee beans as anti-obesity and antihyperlipidemic agents. The separated and combined administration exhibited significant anti-obesity and antihyperlipidemic effects in obese and hyperlipidemic rats, while the combined administration showed more powerful effects. Previous reports on cinnamon, ginger and green coffee as separately administered were thus confirmed; however, this is, to our knowledge, the first report dealing with the combined form of the three plants. Such combined administration might be useful in developing natural food additives to help address obesity and hyperlipidemia.},
 year = {2017}
}

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TY  - JOUR
T1  - Phytochemical Evaluation, Anti-obesity and Antihyperlipidemic Effects of Combined Administration of Green Coffee, Cinnamon and Ginger
AU  - Gehan Fawzy Abdel Raoof
AU  - Khaled Younes Mohamed
AU  - Hala Mahmoud Mohammed
Y1  - 2017/11/08
PY  - 2017
N1  - https://doi.org/10.11648/j.plant.20170505.12
DO  - 10.11648/j.plant.20170505.12
T2  - Plant
JF  - Plant
JO  - Plant
SP  - 80
EP  - 84
PB  - Science Publishing Group
SN  - 2331-0677
UR  - https://doi.org/10.11648/j.plant.20170505.12
AB  - This study aims to evaluate anti-obesity and antihyperlipidemic effects of individual and combined administration of ginger, cinnamon and green coffee on the hyperlipidimic rats. It is the first report dealing with the effects of the combined administration of these three plants as anti-obesity and antihyperlipidemic agents. Sprague-Dawley rats were used, where they divided into 6 groups (7 rats each). Group 1 was kept as a normal control, while the other groups fed on high-fat diet to induce obesity and hyperlipidemia for 4 weeks. Group 2 positive control that was kept obese, while other groups were orally given individual and combined powders of ginger, cinnamon and green coffee in doses 200mg/kg, respectively, for 6 weeks, At the end of the experiment, body weight of rats were recorded. Blood samples were collected for analyses. The results showed that each of individual and combined administration of these plants significantly (P<0.05) decreased the body weight and serum lipids including total lipid, triglyceride and low density lipoprotein when compared with positive control group, while they significantly (P<0.05) increased high density lipoprotein when compared with positive control group. Furthermore, our study showed that the combination of these three plants exhibited better effects than when compared to the individual powder of the plants. In this study we compared the effects of separated and combined administration of cinnamon bark, ginger root, green coffee beans as anti-obesity and antihyperlipidemic agents. The separated and combined administration exhibited significant anti-obesity and antihyperlipidemic effects in obese and hyperlipidemic rats, while the combined administration showed more powerful effects. Previous reports on cinnamon, ginger and green coffee as separately administered were thus confirmed; however, this is, to our knowledge, the first report dealing with the combined form of the three plants. Such combined administration might be useful in developing natural food additives to help address obesity and hyperlipidemia.
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Author Information

Gehan Fawzy Abdel Raoof

Pharmacognosy Department, National Research Centre, Giza, Egypt
Khaled Younes Mohamed

Internal Medicine Department, National Research Centre, Giza, Egypt
Hala Mahmoud Mohammed

Food Industry Department, Faculty of Agriculture, Cairo University, Cairo, Egypt

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Gehan Fawzy Abdel Raoof, Khaled Younes Mohamed, Hala Mahmoud Mohammed. (2017). Phytochemical Evaluation, Anti-obesity and Antihyperlipidemic Effects of Combined Administration of Green Coffee, Cinnamon and Ginger. Plant, 5(5), 80-84. https://doi.org/10.11648/j.plant.20170505.12

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ACS Style

Gehan Fawzy Abdel Raoof; Khaled Younes Mohamed; Hala Mahmoud Mohammed. Phytochemical Evaluation, Anti-obesity and Antihyperlipidemic Effects of Combined Administration of Green Coffee, Cinnamon and Ginger. Plant. 2017, 5(5), 80-84. doi: 10.11648/j.plant.20170505.12

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AMA Style

Gehan Fawzy Abdel Raoof, Khaled Younes Mohamed, Hala Mahmoud Mohammed. Phytochemical Evaluation, Anti-obesity and Antihyperlipidemic Effects of Combined Administration of Green Coffee, Cinnamon and Ginger. Plant. 2017;5(5):80-84. doi: 10.11648/j.plant.20170505.12

Copy | Download

@article{10.11648/j.plant.20170505.12,
  author = {Gehan Fawzy Abdel Raoof and Khaled Younes Mohamed and Hala Mahmoud Mohammed},
  title = {Phytochemical Evaluation, Anti-obesity and Antihyperlipidemic Effects of Combined Administration of Green Coffee, Cinnamon and Ginger},
  journal = {Plant},
  volume = {5},
  number = {5},
  pages = {80-84},
  doi = {10.11648/j.plant.20170505.12},
  url = {https://doi.org/10.11648/j.plant.20170505.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.plant.20170505.12},
  abstract = {This study aims to evaluate anti-obesity and antihyperlipidemic effects of individual and combined administration of ginger, cinnamon and green coffee on the hyperlipidimic rats. It is the first report dealing with the effects of the combined administration of these three plants as anti-obesity and antihyperlipidemic agents. Sprague-Dawley rats were used, where they divided into 6 groups (7 rats each). Group 1 was kept as a normal control, while the other groups fed on high-fat diet to induce obesity and hyperlipidemia for 4 weeks. Group 2 positive control that was kept obese, while other groups were orally given individual and combined powders of ginger, cinnamon and green coffee in doses 200mg/kg, respectively, for 6 weeks, At the end of the experiment, body weight of rats were recorded. Blood samples were collected for analyses. The results showed that each of individual and combined administration of these plants significantly (P<0.05) decreased the body weight and serum lipids including total lipid, triglyceride and low density lipoprotein when compared with positive control group, while they significantly (P<0.05) increased high density lipoprotein when compared with positive control group. Furthermore, our study showed that the combination of these three plants exhibited better effects than when compared to the individual powder of the plants. In this study we compared the effects of separated and combined administration of cinnamon bark, ginger root, green coffee beans as anti-obesity and antihyperlipidemic agents. The separated and combined administration exhibited significant anti-obesity and antihyperlipidemic effects in obese and hyperlipidemic rats, while the combined administration showed more powerful effects. Previous reports on cinnamon, ginger and green coffee as separately administered were thus confirmed; however, this is, to our knowledge, the first report dealing with the combined form of the three plants. Such combined administration might be useful in developing natural food additives to help address obesity and hyperlipidemia.},
 year = {2017}
}

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TY  - JOUR
T1  - Phytochemical Evaluation, Anti-obesity and Antihyperlipidemic Effects of Combined Administration of Green Coffee, Cinnamon and Ginger
AU  - Gehan Fawzy Abdel Raoof
AU  - Khaled Younes Mohamed
AU  - Hala Mahmoud Mohammed
Y1  - 2017/11/08
PY  - 2017
N1  - https://doi.org/10.11648/j.plant.20170505.12
DO  - 10.11648/j.plant.20170505.12
T2  - Plant
JF  - Plant
JO  - Plant
SP  - 80
EP  - 84
PB  - Science Publishing Group
SN  - 2331-0677
UR  - https://doi.org/10.11648/j.plant.20170505.12
AB  - This study aims to evaluate anti-obesity and antihyperlipidemic effects of individual and combined administration of ginger, cinnamon and green coffee on the hyperlipidimic rats. It is the first report dealing with the effects of the combined administration of these three plants as anti-obesity and antihyperlipidemic agents. Sprague-Dawley rats were used, where they divided into 6 groups (7 rats each). Group 1 was kept as a normal control, while the other groups fed on high-fat diet to induce obesity and hyperlipidemia for 4 weeks. Group 2 positive control that was kept obese, while other groups were orally given individual and combined powders of ginger, cinnamon and green coffee in doses 200mg/kg, respectively, for 6 weeks, At the end of the experiment, body weight of rats were recorded. Blood samples were collected for analyses. The results showed that each of individual and combined administration of these plants significantly (P<0.05) decreased the body weight and serum lipids including total lipid, triglyceride and low density lipoprotein when compared with positive control group, while they significantly (P<0.05) increased high density lipoprotein when compared with positive control group. Furthermore, our study showed that the combination of these three plants exhibited better effects than when compared to the individual powder of the plants. In this study we compared the effects of separated and combined administration of cinnamon bark, ginger root, green coffee beans as anti-obesity and antihyperlipidemic agents. The separated and combined administration exhibited significant anti-obesity and antihyperlipidemic effects in obese and hyperlipidemic rats, while the combined administration showed more powerful effects. Previous reports on cinnamon, ginger and green coffee as separately administered were thus confirmed; however, this is, to our knowledge, the first report dealing with the combined form of the three plants. Such combined administration might be useful in developing natural food additives to help address obesity and hyperlipidemia.
VL  - 5
IS  - 5
ER  -

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