Human Immunodeficiency Virus Viral Load Suppression and Associated Factors Among Client on Anti-Retroviral Therapy in Asella Teaching and Referral Hospital, Ethiopia

Abdurrahman Geleto Sado; Solomon Wolde-Mariam Chakso; Girma Worku Obsie

doi:doi:10.11648/j.ijhpebs.20220802.13

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Human Immunodeficiency Virus Viral Load Suppression and Associated Factors Among Client on Anti-Retroviral Therapy in Asella Teaching and Referral Hospital, Ethiopia

Abdurrahman Geleto Sado, Solomon Wolde-Mariam Chakso, Girma Worku Obsie

Published in International Journal of HIV/AIDS Prevention, Education and Behavioural Science (Volume 8, Issue 2)

Received: 5 October 2022 Accepted: 17 November 2022 Published: 29 November 2022

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Abstract

The aim of therapy following treatment failure is to attain and maintain Virological suppressions via the three 90 target by the year 2020 to accelerate reaching epidemic control of those on Anti-Retroviral Therapy (ART) shall be virally suppressed. Objective: The purposed of this study to evaluate Human Immunodeficiency Virus (HIV) on High viral load suppression and factors associated among client on ART in Asella Teaching and Referral Hospital, Arsi Zone, Oromia Regional State, Ethiopia, 2019. Methods: Institution based cross sectional study was done by chart review. A total of 430 study subjects were selected with complete information included in the analysis. The collected data was entered in to Epi info Version 7 software then cleaned data was exported to SPSS version 21 for analysis. All independent variables with at p-value<0.2 in the crude analysis were involved in the multiple logistic regression analysis with 95% CI computed. A P-value<0.05 has considered statistically significant. Result: A total of 430 people living with HIV enrolled in this study was, 356 (82.8%) had not suppressed viral load with the corresponding 95% confidence interval was (79.2, 86.3). People living with HIV enrolled with '''baseline Hgb < 10g/dl [AOR=1.834, 95% CI (1.407, 2.710)], patients having poor adherence [AOR=15.204, 95% CI (8.087, 28.58)] and patients enrolled to care who use substance [AOR=1.6, 95% CI (1.021, 3.118)] were at risky to get high viral load. Conclusion: The findings of this study strongly showed that on treatment viral load suppression rates 17.2% patients had suppressed viral load < 1000 RNAcopies/mL. This proportion falls short of the UNAIDS’ 90% target for on treatment viral suppression. Poor adherence, Hgb level < 10g/dl and substance use were factors that decreases rates of viral load suppression. Therefore, the Human Immunodeficiency Virus (HIV) treatment program can maintain and potentially improve virological treatment outcomes by improving access to targeted viral load testing.

Published in	International Journal of HIV/AIDS Prevention, Education and Behavioural Science (Volume 8, Issue 2)
DOI	10.11648/j.ijhpebs.20220802.13
Page(s)	61-68
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Anti-Retroviral Therapy Asella Referral & Teaching Hospital, Associated Factors, Viral Load Suppression

References

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APA Style

Abdurrahman Geleto Sado, Solomon Wolde-Mariam Chakso, Girma Worku Obsie. (2022). Human Immunodeficiency Virus Viral Load Suppression and Associated Factors Among Client on Anti-Retroviral Therapy in Asella Teaching and Referral Hospital, Ethiopia. International Journal of HIV/AIDS Prevention, Education and Behavioural Science, 8(2), 61-68. https://doi.org/10.11648/j.ijhpebs.20220802.13

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ACS Style

Abdurrahman Geleto Sado; Solomon Wolde-Mariam Chakso; Girma Worku Obsie. Human Immunodeficiency Virus Viral Load Suppression and Associated Factors Among Client on Anti-Retroviral Therapy in Asella Teaching and Referral Hospital, Ethiopia. Int. J. HIV/AIDS Prev. Educ. Behav. Sci. 2022, 8(2), 61-68. doi: 10.11648/j.ijhpebs.20220802.13

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AMA Style

Abdurrahman Geleto Sado, Solomon Wolde-Mariam Chakso, Girma Worku Obsie. Human Immunodeficiency Virus Viral Load Suppression and Associated Factors Among Client on Anti-Retroviral Therapy in Asella Teaching and Referral Hospital, Ethiopia. Int J HIV/AIDS Prev Educ Behav Sci. 2022;8(2):61-68. doi: 10.11648/j.ijhpebs.20220802.13

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@article{10.11648/j.ijhpebs.20220802.13,
  author = {Abdurrahman Geleto Sado and Solomon Wolde-Mariam Chakso and Girma Worku Obsie},
  title = {Human Immunodeficiency Virus Viral Load Suppression and Associated Factors Among Client on Anti-Retroviral Therapy in Asella Teaching and Referral Hospital, Ethiopia},
  journal = {International Journal of HIV/AIDS Prevention, Education and Behavioural Science},
  volume = {8},
  number = {2},
  pages = {61-68},
  doi = {10.11648/j.ijhpebs.20220802.13},
  url = {https://doi.org/10.11648/j.ijhpebs.20220802.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhpebs.20220802.13},
  abstract = {The aim of therapy following treatment failure is to attain and maintain Virological suppressions via the three 90 target by the year 2020 to accelerate reaching epidemic control of those on Anti-Retroviral Therapy (ART) shall be virally suppressed. Objective: The purposed of this study to evaluate Human Immunodeficiency Virus (HIV) on High viral load suppression and factors associated among client on ART in Asella Teaching and Referral Hospital, Arsi Zone, Oromia Regional State, Ethiopia, 2019. Methods: Institution based cross sectional study was done by chart review. A total of 430 study subjects were selected with complete information included in the analysis. The collected data was entered in to Epi info Version 7 software then cleaned data was exported to SPSS version 21 for analysis. All independent variables with at p-value<0.2 in the crude analysis were involved in the multiple logistic regression analysis with 95% CI computed. A P-value<0.05 has considered statistically significant. Result: A total of 430 people living with HIV enrolled in this study was, 356 (82.8%) had not suppressed viral load with the corresponding 95% confidence interval was (79.2, 86.3). People living with HIV enrolled with '''baseline Hgb < 10g/dl [AOR=1.834, 95% CI (1.407, 2.710)], patients having poor adherence [AOR=15.204, 95% CI (8.087, 28.58)] and patients enrolled to care who use substance [AOR=1.6, 95% CI (1.021, 3.118)] were at risky to get high viral load. Conclusion: The findings of this study strongly showed that on treatment viral load suppression rates 17.2% patients had suppressed viral load < 1000 RNAcopies/mL. This proportion falls short of the UNAIDS’ 90% target for on treatment viral suppression. Poor adherence, Hgb level < 10g/dl and substance use were factors that decreases rates of viral load suppression. Therefore, the Human Immunodeficiency Virus (HIV) treatment program can maintain and potentially improve virological treatment outcomes by improving access to targeted viral load testing.},
 year = {2022}
}

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TY  - JOUR
T1  - Human Immunodeficiency Virus Viral Load Suppression and Associated Factors Among Client on Anti-Retroviral Therapy in Asella Teaching and Referral Hospital, Ethiopia
AU  - Abdurrahman Geleto Sado
AU  - Solomon Wolde-Mariam Chakso
AU  - Girma Worku Obsie
Y1  - 2022/11/29
PY  - 2022
N1  - https://doi.org/10.11648/j.ijhpebs.20220802.13
DO  - 10.11648/j.ijhpebs.20220802.13
T2  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JF  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JO  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
SP  - 61
EP  - 68
PB  - Science Publishing Group
SN  - 2575-5765
UR  - https://doi.org/10.11648/j.ijhpebs.20220802.13
AB  - The aim of therapy following treatment failure is to attain and maintain Virological suppressions via the three 90 target by the year 2020 to accelerate reaching epidemic control of those on Anti-Retroviral Therapy (ART) shall be virally suppressed. Objective: The purposed of this study to evaluate Human Immunodeficiency Virus (HIV) on High viral load suppression and factors associated among client on ART in Asella Teaching and Referral Hospital, Arsi Zone, Oromia Regional State, Ethiopia, 2019. Methods: Institution based cross sectional study was done by chart review. A total of 430 study subjects were selected with complete information included in the analysis. The collected data was entered in to Epi info Version 7 software then cleaned data was exported to SPSS version 21 for analysis. All independent variables with at p-value<0.2 in the crude analysis were involved in the multiple logistic regression analysis with 95% CI computed. A P-value<0.05 has considered statistically significant. Result: A total of 430 people living with HIV enrolled in this study was, 356 (82.8%) had not suppressed viral load with the corresponding 95% confidence interval was (79.2, 86.3). People living with HIV enrolled with '''baseline Hgb < 10g/dl [AOR=1.834, 95% CI (1.407, 2.710)], patients having poor adherence [AOR=15.204, 95% CI (8.087, 28.58)] and patients enrolled to care who use substance [AOR=1.6, 95% CI (1.021, 3.118)] were at risky to get high viral load. Conclusion: The findings of this study strongly showed that on treatment viral load suppression rates 17.2% patients had suppressed viral load < 1000 RNAcopies/mL. This proportion falls short of the UNAIDS’ 90% target for on treatment viral suppression. Poor adherence, Hgb level < 10g/dl and substance use were factors that decreases rates of viral load suppression. Therefore, the Human Immunodeficiency Virus (HIV) treatment program can maintain and potentially improve virological treatment outcomes by improving access to targeted viral load testing.
VL  - 8
IS  - 2
ER  -

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Author Information

Abdurrahman Geleto Sado

Asella Town Health Office, Asella, Ethiopia
Solomon Wolde-Mariam Chakso

Asella Town Health Office, Asella, Ethiopia
Girma Worku Obsie

Department of Public Health College of Health Science, Arsi University, Assela, Ethiopia

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APA Style

Abdurrahman Geleto Sado, Solomon Wolde-Mariam Chakso, Girma Worku Obsie. (2022). Human Immunodeficiency Virus Viral Load Suppression and Associated Factors Among Client on Anti-Retroviral Therapy in Asella Teaching and Referral Hospital, Ethiopia. International Journal of HIV/AIDS Prevention, Education and Behavioural Science, 8(2), 61-68. https://doi.org/10.11648/j.ijhpebs.20220802.13

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ACS Style

Abdurrahman Geleto Sado; Solomon Wolde-Mariam Chakso; Girma Worku Obsie. Human Immunodeficiency Virus Viral Load Suppression and Associated Factors Among Client on Anti-Retroviral Therapy in Asella Teaching and Referral Hospital, Ethiopia. Int. J. HIV/AIDS Prev. Educ. Behav. Sci. 2022, 8(2), 61-68. doi: 10.11648/j.ijhpebs.20220802.13

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AMA Style

Abdurrahman Geleto Sado, Solomon Wolde-Mariam Chakso, Girma Worku Obsie. Human Immunodeficiency Virus Viral Load Suppression and Associated Factors Among Client on Anti-Retroviral Therapy in Asella Teaching and Referral Hospital, Ethiopia. Int J HIV/AIDS Prev Educ Behav Sci. 2022;8(2):61-68. doi: 10.11648/j.ijhpebs.20220802.13

Copy | Download

@article{10.11648/j.ijhpebs.20220802.13,
  author = {Abdurrahman Geleto Sado and Solomon Wolde-Mariam Chakso and Girma Worku Obsie},
  title = {Human Immunodeficiency Virus Viral Load Suppression and Associated Factors Among Client on Anti-Retroviral Therapy in Asella Teaching and Referral Hospital, Ethiopia},
  journal = {International Journal of HIV/AIDS Prevention, Education and Behavioural Science},
  volume = {8},
  number = {2},
  pages = {61-68},
  doi = {10.11648/j.ijhpebs.20220802.13},
  url = {https://doi.org/10.11648/j.ijhpebs.20220802.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhpebs.20220802.13},
  abstract = {The aim of therapy following treatment failure is to attain and maintain Virological suppressions via the three 90 target by the year 2020 to accelerate reaching epidemic control of those on Anti-Retroviral Therapy (ART) shall be virally suppressed. Objective: The purposed of this study to evaluate Human Immunodeficiency Virus (HIV) on High viral load suppression and factors associated among client on ART in Asella Teaching and Referral Hospital, Arsi Zone, Oromia Regional State, Ethiopia, 2019. Methods: Institution based cross sectional study was done by chart review. A total of 430 study subjects were selected with complete information included in the analysis. The collected data was entered in to Epi info Version 7 software then cleaned data was exported to SPSS version 21 for analysis. All independent variables with at p-value<0.2 in the crude analysis were involved in the multiple logistic regression analysis with 95% CI computed. A P-value<0.05 has considered statistically significant. Result: A total of 430 people living with HIV enrolled in this study was, 356 (82.8%) had not suppressed viral load with the corresponding 95% confidence interval was (79.2, 86.3). People living with HIV enrolled with '''baseline Hgb < 10g/dl [AOR=1.834, 95% CI (1.407, 2.710)], patients having poor adherence [AOR=15.204, 95% CI (8.087, 28.58)] and patients enrolled to care who use substance [AOR=1.6, 95% CI (1.021, 3.118)] were at risky to get high viral load. Conclusion: The findings of this study strongly showed that on treatment viral load suppression rates 17.2% patients had suppressed viral load < 1000 RNAcopies/mL. This proportion falls short of the UNAIDS’ 90% target for on treatment viral suppression. Poor adherence, Hgb level < 10g/dl and substance use were factors that decreases rates of viral load suppression. Therefore, the Human Immunodeficiency Virus (HIV) treatment program can maintain and potentially improve virological treatment outcomes by improving access to targeted viral load testing.},
 year = {2022}
}

Copy | Download

TY  - JOUR
T1  - Human Immunodeficiency Virus Viral Load Suppression and Associated Factors Among Client on Anti-Retroviral Therapy in Asella Teaching and Referral Hospital, Ethiopia
AU  - Abdurrahman Geleto Sado
AU  - Solomon Wolde-Mariam Chakso
AU  - Girma Worku Obsie
Y1  - 2022/11/29
PY  - 2022
N1  - https://doi.org/10.11648/j.ijhpebs.20220802.13
DO  - 10.11648/j.ijhpebs.20220802.13
T2  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JF  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JO  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
SP  - 61
EP  - 68
PB  - Science Publishing Group
SN  - 2575-5765
UR  - https://doi.org/10.11648/j.ijhpebs.20220802.13
AB  - The aim of therapy following treatment failure is to attain and maintain Virological suppressions via the three 90 target by the year 2020 to accelerate reaching epidemic control of those on Anti-Retroviral Therapy (ART) shall be virally suppressed. Objective: The purposed of this study to evaluate Human Immunodeficiency Virus (HIV) on High viral load suppression and factors associated among client on ART in Asella Teaching and Referral Hospital, Arsi Zone, Oromia Regional State, Ethiopia, 2019. Methods: Institution based cross sectional study was done by chart review. A total of 430 study subjects were selected with complete information included in the analysis. The collected data was entered in to Epi info Version 7 software then cleaned data was exported to SPSS version 21 for analysis. All independent variables with at p-value<0.2 in the crude analysis were involved in the multiple logistic regression analysis with 95% CI computed. A P-value<0.05 has considered statistically significant. Result: A total of 430 people living with HIV enrolled in this study was, 356 (82.8%) had not suppressed viral load with the corresponding 95% confidence interval was (79.2, 86.3). People living with HIV enrolled with '''baseline Hgb < 10g/dl [AOR=1.834, 95% CI (1.407, 2.710)], patients having poor adherence [AOR=15.204, 95% CI (8.087, 28.58)] and patients enrolled to care who use substance [AOR=1.6, 95% CI (1.021, 3.118)] were at risky to get high viral load. Conclusion: The findings of this study strongly showed that on treatment viral load suppression rates 17.2% patients had suppressed viral load < 1000 RNAcopies/mL. This proportion falls short of the UNAIDS’ 90% target for on treatment viral suppression. Poor adherence, Hgb level < 10g/dl and substance use were factors that decreases rates of viral load suppression. Therefore, the Human Immunodeficiency Virus (HIV) treatment program can maintain and potentially improve virological treatment outcomes by improving access to targeted viral load testing.
VL  - 8
IS  - 2
ER  -

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